The Gut Microbiome’s Role in Gout & Hyperuricemia

What causes gout? Most people associate it with diet—too much red meat, alcohol, or sugar. But new research suggests the gut microbiome may play a bigger role in how the body processes uric acid, which can lead to gout.

In the latest 5-Minute Focus episode of The Wellness Pharmacist, I break down a study published in Arthritis & Rheumatology on January 19, 2025. The findings reveal that gut bacteria influence uric acid metabolism, and imbalances in the microbiome (dysbiosis) may contribute to hyperuricemia and gout flares.

Key Takeaways from the Study:

✔️ Certain gut bacteria help break down purines, compounds that contribute to uric acid production.
✔️ People with gout often have fewer beneficial gut bacteria and more inflammatory microbes.
✔️ Probiotics, prebiotics, and dietary changes may help regulate uric acid levels and reduce inflammation.

💡 Bottom line: The gut-joint connection is real! Supporting gut health with fiber-rich foods, probiotics, and balanced nutrition could be a game-changer for gout management.

👉 Listen to the full episode: https://rss.com/podcasts/the-wellness-pharmacist/1937248/
👉 Watch on YouTube: https://youtu.be/K0PowaxDFpo

What are your thoughts on this gut-gout connection? Drop your questions in the comments!

If you need a medical writer with pharmacist expertise, contact me at innovationsmedicationmgmt@gmail.com.

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About the author

Hi! My name is Dr. Kat, I’m a clinical pharmacist and health advocate from the USA and founder of Innovations Medication Management. In this blog I share my health and wellness tips and give you actionable steps in your health journey. You can watch my videos/podcast that I organize on chronic illnesses.